A new episodic ataxia syndrome with linkage to chromosome 19q13.
نویسندگان
چکیده
BACKGROUND Multiple episodic ataxia phenotypes and genotypes have been described. OBJECTIVE To describe a new episodic ataxia syndrome. DESIGN Genomewide linkage analysis with dense single nucleotide polymorphism arrays. SETTING University clinic. Patients Family with lifelong episodes of ataxia and normal interictal examination results. RESULTS Suggestive linkage (logarithm of odds score, 3.27) to a 10-centimorgan region on chromosome 19q13. CONCLUSION A new dominantly inherited episodic ataxia syndrome is linked to chromosome 19q.
منابع مشابه
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ورودعنوان ژورنال:
- Archives of neurology
دوره 64 5 شماره
صفحات -
تاریخ انتشار 2007